‘You could never eliminate the possibility of dream sequences and flashbacks,’ Moffat said in an interview, ‘But will the Doctor see them again? No.’
He said he was pleased by the 'proper ending' given in The Angels Take Manhattan.
‘Bringing back things just gives you sequel-itis. Just end it and get out. Heaven knows if they’ll appear in some form of flashback – I have no plans to do that I have to say – but the story of Amy and The Doctor is definitively over.’
Looks like another set of old companions crossed off the list for the 50th, then!